A substance made from the leaves, sap, and fruit of the grape vine plant. Grapeseed extract (also spelled as grape seed extract) may have some health benefits; some studies show that a fairly large dose of the extract can reduce swelling, and it may have anti-inflammatory and antibacterial characteristics when taken as a supplement.

It also has high levels of antioxidants, and when applied topically, grape seed extract may accelerate the skin’s natural healing processes. However, these benefits are not firmly established, and more research needs to be completed to verify these effects.

Grapeseed extract is used in some lubricants and massage oils for its apparent skin-friendly benefits. It is considered a safe ingredient, although it can cause mild itching in large amounts.