Also known as polydimethylsiloxane, dimethicone is a silicone compound that is similar in composition to plastic. It is a popular ingredient in personal lubricant products. Lubricants that use dimethicone are more effective than water-based lubricants due to the long-lasting slipperiness of dimethicone as well as the water repellent effect. Silicone-based lubricants are safe for latex condom use, unlike oil-based lubricants. Dimethicone is extremely well-tolerated, and very few people experience irritation or other side effects when using pure silicone lubricants.